CA1 interneuron: K currents (Lien et al 2002)

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Contributor:NIJC Administrator (nijcadmin)  |  Created Date: Mar 16, 2011 17:31:12  |  Visits:1593  |  Runs:24
Free Keywords: CA1 pyramidal neurons, potassium channel
ID 163
Title CA1 interneuron: K currents (Lien et al 2002)
Free Keywords CA1 pyramidal neurons, potassium channel
Description This content is a demonstration for slow and fast K-DR, and K-A potassium currents in inhibitory interneurones of stratum oriens-alveus of the hippocampal CA1 region.

Running the simulation will show the activation and inactivation steady-states, the time constants, and a family of curves generated modeling the same protocols used for Figs.5A-6A-7A of the paper.

Markers show a few of the experimental values for the time constants derived from Figs.5C-6C-7C-7D.

For both the fast and slow KDR currents an inactivation time constant of 1sec is assumed. KA recovery from inactivation is not implemented.
Last Modified Date Mar 22, 2013 15:00:08
Created Date Mar 16, 2011 17:31:12
Contributor NIJC Administrator (nijcadmin)
Item Type Online Simulation
Change Log(History)
Mar 22, 2013 Modified; Contents URL.
Mar 15, 2012 Modified; Description, Free Keywords, Preview, Simulator Name.
Mar 24, 2011 Modified; Index.
Mar 23, 2011 Modified; Preview, Simulator.
Model Contents URL http://senselab.med.yale.edu/modeldb/ShowModel.asp?model=20015
Hits:1
Model Site Name ModelDB
Simulator Name Neuron
Simulator Version
Index
/ Public / Title / A-E


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