Supported by INCF Japan NodeFluctuating synaptic conductances recreate in-vivo-like activity (Destexhe et al 2001)
登録者:NIJC管理者 (nijcadmin)
|
作成日: Mar 17, 2011 14:34:34
|
来訪者数:2100
|
実行回数:49
フリーキーワード: Action Potentials, Animals, Cats, Cell Compartmentation, Dendrites, Glutamic Acid, Ion Channels, Neurological Models, Neocortex, Nerve Net, Neural Inhibition, Organ Culture Techniques, Patch-Clamp Techniques, Pyramidal Cells, Sprague-Dawley Rats, AMPA/drug effects Receptors, AMPA/physiology Receptors, Stochastic Processes, Synapses, Synaptic Transmission, Tetrodotoxin, gamma-Aminobutyric Acid
| ID | 249 | ||||||||
| タイトル | Fluctuating synaptic conductances recreate in-vivo-like activity (Destexhe et al 2001) | ||||||||
| フリーキーワード | Action Potentials, Animals, Cats, Cell Compartmentation, Dendrites, Glutamic Acid, Ion Channels, Neurological Models, Neocortex, Nerve Net, Neural Inhibition, Organ Culture Techniques, Patch-Clamp Techniques, Pyramidal Cells, Sprague-Dawley Rats, AMPA/drug effects Receptors, AMPA/physiology Receptors, Stochastic Processes, Synapses, Synaptic Transmission, Tetrodotoxin, gamma-Aminobutyric Acid | ||||||||
| 概要 | This model (and experiments) reported in Destexhe, Rudolh, Fellous, and Sejnowski (2001) support the hypothesis that many of the characteristics of cortical neurons in vivo can be explained by fast glutamatergic and GABAergic conductances varying stochastically. Some of these cortical neuron characteristics of fluctuating synaptic origin are a depolarized membrane potential, the presence of high-amplitude membrane potential fluctuations, a low input resistance and irregular spontaneous firing activity. In addition, the point-conductance model could simulate the enhancement of responsiveness due to background activity. For more information please contact Alain Destexhe. email: Destexhe@iaf.cnrs-gif.fr Once the menu and graphics interface has appeared, click on "Init and Run" to start the simulation... Reference: Destexhe A, Rudolph M, Fellous JM, Sejnowski TJ (2001) Fluctuating synaptic conductances recreate in vivo-like activity in neocortical neurons. Neuroscience 107:13-24 |
||||||||
| 最終更新日 | Mar 22, 2013 13:07:51 | ||||||||
| 作成日 | Mar 17, 2011 14:34:34 | ||||||||
| 登録者 | NIJC管理者 (nijcadmin) | ||||||||
| アイテムタイプ | Online Simulation | ||||||||
| 更新履歴 |
|
||||||||
| モデルコンテンツへのURL |
http://senselab.med.yale.edu/modeldb/ShowModel.asp?model=8115
ヒット数:2 |
||||||||
| 登録PF・DB | ModelDB | ||||||||
| シミュレータ | Neuron | ||||||||
| シミュレータのバージョン | |||||||||
| Index |
|
