A dynamical model of the basal ganglia (Leblois et al 2006)

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Contributor:NIJC Administrator (nijcadmin)  |  Created Date: Mar 16, 2011 14:35:37  |  Visits:2154  |  Runs:132
Free Keywords: Oscillations, Spatio-temporal Activity Patterns, Simplified models, Rate-coding model neurons
ID 58
Title A dynamical model of the basal ganglia (Leblois et al 2006)
Free Keywords Oscillations, Spatio-temporal Activity Patterns, Simplified models, Rate-coding model neurons
Description We propose a new model for the function and dysfunction of the basal ganglia (BG). The basal ganglia are a set of cerebral structures involved in motor control which dysfunction causes high-incidence pathologies such as Parkinson's disease (PD). Their precise motor functions remain unknown. The classical model of the BG that allowed for the discovery of new treatments for PD seems today outdated in several respects. Based on experimental observations, our model proposes a simple dynamical framework for the understanding of how BG may select motor programs to be executed. Moreover, we explain how this ability is lost and how tremor-related oscillations in neuronal activity may emerge in PD.

Simulation time: 2 min
Results: At the end of simulation the unit response will show up.
Last Modified Date Mar 21, 2013 17:14:39
Created Date Mar 16, 2011 14:35:37
Contributor NIJC Administrator (nijcadmin)
Item Type Online Simulation
Change Log(History)
Mar 21, 2013 Modified; Contents URL.
Feb 2, 2012 Modified; Description, Free Keywords, Simulator Version.
Mar 24, 2011 Modified; Index.
Mar 23, 2011 Modified; Preview, Simulator.
Model Contents URL http://senselab.med.yale.edu/modeldb/ShowModel.asp?model=64255
Hits:11
Model Site Name ModelDB
Simulator Name
Simulator Version C/C++
Index
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